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Thursday, 18 August 2011 04:59

Nitrocompounds, Aromatic: Health Hazards

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Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

1-CHLORO-2,4-DINITROBEN­ZENE    97-00-7

eyes; skin; resp tract

skin; eyes

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing, nausea, vomiting, disturbed vision 

Skin: may be absorbed, redness, pain  

Eyes: redness, pain  

Ingestion: abdominal pain, blue skin, dizziness, headache, laboured breathing, nausea, vomiting

1-CHLORO-2-NITROBENZENE 88-73-3

eyes; skin; resp tract; blood

blood; liver; kidneys; spleen

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, nausea, shortness of breath

Skin: may be absorbed, redness

Eyes: redness, pain

1-CHLORO-4-NITROBENZENE 100-00-5

blood

skin; blood

Inhalation: headache, faintness, vertigo, weakness    

Skin: may be absorbed

Blood; liver; kidneys; CVS; spleen; bone marrow; repro sys (in animals: vascular & liver tumors) Inh; abs; ing; con

Anoxia; unpleasant taste; anemia; methemo; in animals: hema, hemog; spleen, kidney, bone marrow changes; repro effects; (carc)

1,2-DICHLORO-3-NITROBEN­ZENE    3209-22-1

blood

skin; liver; kidneys

Inhalation: blue lips or finger nails  

Skin: may be absorbed, redness, blue lips, blue fingernails

Ingestion: blue lips or fingernails, blue skin, confusion, headache, vomiting, weakness

1,2-DICHLORO-4-NITROBEN­ZENE    99-54-7

eyes; skin; resp tract; lungs

skin; kidneys; liver

Inhalation: blue lips or finger nails, burning sensation of the throat, headache, shortness of breath

Skin: may be absorbed, redness, burning sensation, pain, blue lips or fingernails  

Eyes: redness, pain      

Ingestion: blue lips or fingernails

2,4-DICHLORO-1-NITROBEN­ZENE    611-06-3

blood

liver; kidneys

Inhalation: blue lips or finger nails

Skin: may be absorbed, redness, blue lips, blue fingernails    

Eyes: redness

Ingestion: blue lips or fingernails, blue skin, confusion, headache, vomiting, weakness

1,3-DINITROBENZENE     99-65-0

eyes; skin; resp tract

liver; may impair male fertility

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing, weakness, burning sensation in the mouth, dry throat, thirst, disturbed vision  

Skin: may be absorbed, redness, skin burns, yellowing of skin

Eyes: redness, burns      

Ingestion: abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

Blood; liver; CVS; eyes; CNS; skin Inh; abs; ing; con

Anoxia, cyan; vis dist, central scotomas; bad taste, burning mouth, dry throat, thirst; yellowing hair, skin; anemia; liver damage

DINITROBENZENE     25154-54-5

eyes; skin; resp tract; lungs; blood

liver; may impair male fertility

Inhalation: blue lips or finger nails, blue skin, burning sensation, dizziness, headache, laboured breathing, sore throat, weakness, disturbed vision

Skin: may be absorbed, redness, yellowing of skin

Eyes: redness

Ingestion: abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

o-DINITROBENZENE     528-29-0

eyes; skin; resp tract; lungs; blood

liver

Inhalation: blue lips or finger nails, blue skin, burning sensation, dizziness, headache, laboured breathing, weakness, disturbed vision

Skin: may be absorbed      

Eyes: redness

Ingestion: Abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

Blood; liver; CVS; eyes; CNS; skin Inh; abs; ing; con

Anoxia, cyan; vis dist, central scotomas; bad taste, burning mouth, dry throat, thirst; yellowing hair, skin; anemia; liver damage

p-DINITROBENZENE     100-25-4

eyes; skin; resp tract

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing, weakness, burning sensation in the mouth, dry throat, thirst, disturbed vision

Skin: may be absorbed, redness, yellowing of skin

Eyes: redness, burns      

Ingestion: abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

Blood; liver; CVS; eyes; CNS; skin Inh; abs; ing; con

Anoxia, cyan; vis dist, central scotomas; bad taste, burning mouth, dry throat, thirst; yellowing hair, skin; anemia; liver damage

2,4-DINITROPHENOL       51-28-5

GI tract

skin; CNS; blood; eyes;

Inhalation: sweating, palpitations, nausea, vomiting, collapse and death Skin: may be absorbed

DINITROTOLUENE     25321-14-6

blood

liver; male and female fertility

Inhalation: drowsiness, nausea, vomiting, weakness    

Skin: may be absorbed, blue lips or fingernails, blue skin, methemoglobin skin

Blood; liver; CVS; repro sys (in animals: liver, skin & kidney tumors) Inh; abs; ing; con

Anoxia, cyan; anemia, jaun; repro effects (carc)

2,3-DINITROTOLUENE     602-01-7

CNS; CVS; blood

Skin: may be absorbed

Ingestion: blue lips or fingernails; headache, nausea, sore throat; vomiting

2,4-DINITROTOLUENE     121-14-2

CNS; CVS; blood

Inhalation: blue lips or fingernails, headache, nausea, sore throat, vomiting  

Skin: may be absorbed Ingestion: blue lips or fingernails, headache, nausea, sore throat, vomiting

2,6-DINITROTOLUENE     606-20-2

blood

possibly carcinogenic to humans

Inhalation: blue lips or finger nails, blue skin, diarrhoea, dizziness, drowsiness    

Skin: may be absorbed

3,4-DINITROTOLUENE     610-39-9

CNS; CVS; blood;

Skin: may be absorbed

Ingestion: blue lips or fingernails, headache, nausea, sore throat, vomiting

NITROBENZENE 98-95-3

eyes; blood; CNS

skin; blood; liver; CNS; spleen; may impair male fertility

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, nausea, unconsciousness, weakness  

Skin: may be absorbed

Blood; liver; kidneys; CVS; skin; eyes; repro sys Inh; abs; ing; con

Irrit eyes, skin, anoxia; derm; anemia; methemo; in animals: liver, kidney damage; testicular effects

4-NITRODIPHENYLAMINE     836-30-6

eyes; skin; resp tract; blood; brain

blood

Inhalation: burning sensation, cough, sore throat, see ingestion    

Skin: see ingestion    

Eyes: redness, pain    

Ingestion: blue lips or fingernails, blue skin, dizziness, headache, laboured breathing

NITROFEN         1836-75-5

eyes; skin; resp tract

skin; blood; CNS; human reproduction system

Inhalation: cough, laboured breathing, sore throat        

Skin: redness, pain          

Eyes: redness, pain, blurred vision  

Ingestion: abdominal pain

o-NITROTOLUENE           88-72-2

eyes; skin; resp tract; blood

liver; blood

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, sore throat        

Skin: may be absorbed, redness, pain

Eyes: redness, pain    

Ingestion: abdominal pain, blue lips or fingernails, blue skin, dizziness, headache, laboured breathing

Blood; CNS; CVS; skin; GI tract Inh; abs; ing; con

Anoxia, cyan; head, weak, dizz; ataxia; dysp; tacar; nau, vomit

p-NITROPHENOL     100-02-7

eyes; skin; resp tract; CNS; blood; kidneys

CNS; liver; kidneys; blood;

Inhalation: blue skin, dizziness, headache, fever, nausea, shortness of breath, weakness, perspiration

Skin: may be absorbed, redness, scabs

Eyes: redness, pain    

Ingestion: burning pain in mouth and throat, abdominal pain, dizziness, unconsciousness

p-NITROTOLUENE           99-99-0

eyes; skin; resp tract

liver; kidneys

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, sore throat        

Skin: may be absorbed, redness, pain

Eyes: redness, pain    

Ingestion: abdominal pain, blue lips or fingernails, blue skin, dizziness, headache, laboured breathing, sore throat, unconsciousness

Blood; CNS; CVS; skin; GI tract Inh; abs; ing; con

Anoxia, cyan; head, weak, dizz; ataxia; dysp; tacar; nau, vomit

PICRIC ACID      88-89-1

eyes; skin

skin

Inhalation: cough, sore throat, weakness

Skin: may be absorbed, redness    

Eyes: redness, pain    

Ingestion: diarrhoea, dizziness, headache, nausea, vomiting

Kidneys; liver; blood; skin; eyes Inh; abs; ing; con

Irrit eyes, skin; sens derm; yellow-stained hair, skin; weak, myalgia, anuria, polyuria; bitter taste, GI dist; hepatitis, hema, album, neph

TETRYL 479-45-8

eyes; skin; resp tract; kidneys; liver; blood

skin

Inhalation: sleeplessness, cough, headache, sore throat, nosebleeds

Skin: redness, yellow stains of skin and hair

Eyes: redness, pain    

Ingestion: abdominal pain, dizziness, headache, nausea

Resp sys; eyes; CNS; skin; liver; kidneys Inh; abs; ing; con

Sens derm, itch, eryt; edema on nasal folds, cheeks, neck; kera; sneez; anemia; ftg; cough, coryza; irrity; mal, head, lass, insom; nau, vomit; liver, kidney damage

2,4,6-TRINITROTOLUENE     118-96-7

eyes; skin; resp tract; blood

liver; blood; eyes

Eyes: redness, pain

Blood; liver; eyes; CVS; CNS; kidneys; skin; resp sys Inh; abs; ing; con

Irrit skin, muc memb; liver damage, jaun; cyan; sneez; cough, sore throat; peri neur, musc pain; kidney damage; cataract; sens derm; leucyt; anemia; card irreg

 

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Read 3928 times Last modified on Friday, 09 December 2011 18:05

Contents

Preface
Part I. The Body
Part II. Health Care
Part III. Management & Policy
Part IV. Tools and Approaches
Part V. Psychosocial and Organizational Factors
Part VI. General Hazards
Part VII. The Environment
Part VIII. Accidents and Safety Management
Part IX. Chemicals
Part X. Industries Based on Biological Resources
Part XI. Industries Based on Natural Resources
Part XII. Chemical Industries
Part XIII. Manufacturing Industries
Part XIV. Textile and Apparel Industries
Part XV. Transport Industries
Part XVI. Construction
Part XVII. Services and Trade
Part XVIII. Guides
Guide to Occupations
Guide to Chemicals
Resources
Guide to Units and Abbreviations