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Friday, 12 August 2011 01:20

Phenols & Phenolic Compounds: Health Hazards

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Chemical Name    

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

CATECHOL        120-80-9

eyes; skin; resp tract; GI tracts; CNS; blood

skin

Inhalation: cough, laboured breathing

Skin: may be absorbed, redness

Eyes: redness, severe deep burns

Ingestion: abdominal pain, diarrhoea, vomiting,

Eyes; skin; resp sys; CNS; kidneys Inh; abs; ing; con

Irrit eyes, skin, resp sys; skin sens, derm; lac, burned eyes; convuls, incr BP, kidney inj

p-CHLOROPHENOL     106-48-9

eyes; skin; resp. tract; CNS; bladder

liver; lungs; kidneys; blood; heart

Inhalation: cough, dizziness, headache, laboured breathing, sore throat

Skin: may be absorbed, redness

Eyes: redness

Ingestion: abdominal pain

o-CRESOL         95-48-7

eyes; skin; resp tract; lungs; CNS

skin; lungs; liver; kidneys

Inhalation: burning sensation, cough, headache, laboured breathing, nausea, vomiting

Skin: may be absorbed, redness, pain, blisters

Eyes: redness, pain, severe deep burns

Ingestion: abdominal cramps, burning sensation, collapse

Eyes, skin, resp sys, CNS, liver, kidneys, pancreas, CVS Inh; abs; ing; con

Irrit eyes, skin, muc memb; CNS effects: conf, depres, resp fail; dysp, irreg rapid resp, weak pulse; eye, skin burns; derm; lung, liver, kidney, pancreas damage

m-CRESOL         108-39-4

CNS

skin; lungs; liver; kidneys; CNS

Inhalation: cough, headache, laboured breathing, nausea, unconsciousness

Skin: may be absorbed, roughness

Eyes: severe deep burns

Ingestion: dizziness, dullness, headache, unconsciousness

Eyes; skin; resp sys; CNS; liver; kidneys; CVS; pancreas Inh; abs; ing; con

Irrit eyes, skin, muc memb; CNS effects: conf, depres, resp fail; dysp, irreg rapid resp, weak pulse; eye, skin burns; derm; lung, liver, kidney, pancreas damage

p-CRESOL         106-44-5

eyes; skin; resp tract; lungs; CNS

skin; lungs; liver; kidneys

Inhalation: burning sensation, cough, headache, laboured breathing, nausea, vomiting

Skin: may be absorbed, redness, pain, blisters

Eyes: redness, pain, severe deep burns

Ingestion: abdominal cramps, burning sensation, collapse

Eyes, skin; resp sys; CNS; liver; kidneys; pancreas; CVS Inh; abs; ing; con

Irrit eyes, skin, muc memb; CNS effects: conf, depres, resp fail; dysp, irreg rapid resp, weak pulse; eye, skin burns; derm; lung, liver, kidney, pancreas damage

CRESOL, ALL ISOMERS     1319-77-3

eyes; skin; resp tract; lungs; CNS

skin; lungs; kidneys; liver

Inhalation: confusion, cough, dizziness, headache, shortness of breath, sore throat, unconsciousness, weakness, US NIOSH Symptoms may be delayed

Skin: may cause toxic effects within 20-30 minutes after skin contact, may be absorbed, redness, serious skin burns, pain

Eyes: irritation, pain, severe deep burns

Ingestion: abdominal pain, diarrhoea, vomiting

2,6-DI-tert-BUTYL-p-CRESOL     128-37-0

eyes; skin; resp tract

skin

Inhalation: cough, sore throat

Skin: may be absorbed, redness, pain

Eyes: redness, pain

Ingestion: abdominal pain, diarrhoea, dizziness, headache, vomiting

Eyes, skin Inh; ing; con

Irrit eyes, skin; in animals: decr growth rate, incr liver weight

2,4-DICHLOROPHENOL     120-83-2

Ingestion: dizziness, headache, convulsion, body temperature change

2,5-DICHLOROPHENOL     583-78-8

eyes; skin; resp. tract

Inhalation: see ingestion

Skin: may be absorbed, redness, skin burns, pain

Eyes: redness, pain, severe deep burns

Ingestion: abdominal pain, burning sensation, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting, weakness, loss of coordination

3,5-DICHLOROPHENOL     591-35-5

skin; eyes; resp. tract

Inhalation: see ingestion

Skin: may be absorbed, redness, skin burns, pain

Eyes: redness, pain

Ingestion: abdominal pain, burning sensation, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting, weakness, loss of coordination

DINITRO-o-CRESOL     534-52-1

CVS; endocrine sys; eyes Inh; abs; ing; con

Sense of well being; head, fever, lass, profuse sweat, profuse thirst, tacar, hyperpnea, cough, short breath, coma

HYDROQUINONE     123-31-9

eyes; skin; resp tract

skin

Inhalation: cough, laboured breathing

Skin: redness

Eyes: redness, pain, blurred vision

Ingestion: blue skin, dizziness, headache, nausea, shortness of breath, convulsions, vomiting, ringing in the ears

Eyes; resp sys; skin; CNS Inh; ing; con

Irrit eyes, conj, kera; CNS excitement; colored urine, nau, dizz, suffocation, rapid breath; musc twitch, delirium; collapse; skin irrit, sens, derm

2-HYDROXYBIPHENYL    90-43-7

eyes; skin; resp tract

Inhalation: see ingestion

Skin: redness

Eyes: redness

Ingestion: abdominal cramps, abdominal pain, cough, laboured breathing

NONYLPHENOL, ALL ISOMERS          25154-52-3

eyes; skin; resp tract; lungs

Inhalation: burning sensation, cough, laboured breathing, sore throat, unconsciousness

Skin: redness, skin burns, pain

Eyes: redness, pain, blurred vision

Ingestion: abdominal pain, diarrhoea, nausea, sore throat

PENTACHLOROPHENOL  87-86-5

eyes; skin; resp. tract; lungs; heart

skin; lungs; CNS liver; kidneys

Inhalation: cough, dizziness, drowsiness, headache, laboured breathing, sore throat

Skin: may be absorbed, redness, blisters

Eyes: redness, pain

Ingestion: abdominal cramps, diarrhoea, nausea, unconsciousness, vomiting, weakness

CVS; resp sys; eyes; liver; kidneys; skin; CNSInh; abs; ing; con

Irrit eyes, nose, throat; sneez, cough; weak, anor, low-wgt; sweat; head, dizz; nau, vomit; dysp, chest pain; high fever; derm

PENTACHLOROPHENOL, SODIUM SALT    131-52-2

eyes; skin; resp. tract; lungs

skin; CNS; lungs; liver; kidneys

Inhalation: cough, dizziness, drowsiness, headache, perspiration, laboured breathing, sore throat

Skin: may be absorbed, redness, skin burns, burning sensation

Eyes: redness, pain, loss of vision

Ingestion: fever, perspiration, excitement, convulsion, coma

PHENOL            108-95-2

eyes; skin; resp tract; lungs; CNS; liver; kidneys

skin; kidneys; liver

Inhalation: burning sensation, cough, dizziness, headache, nausea, shortness of breath, unconsciousness, vomiting, US NIOSH Symptoms may be delayed

Skin: may be absorbed, serious skin burns, shock, collapse, coma, convulsion, local anesthetic effect, death

Eyes: permanent loss of vision, severe deep burns

Ingestion: abdominal pain, convulsions, diarrhoea, shock or collapse, sore throat, smoky, greenish-dark urine,

Liver; kidneys; skin; eyes, resp sys Inh; abs; ing; con

Irrit eyes, nose, throat; anor, low-wgt; weak, musc ache, pain; dark urine; cyan; liver, kidney damage; skin burns; derm; ochronosis; tremor, convuls, twitch

PYROGALLIC ACID         87-66-1

eyes; skin; resp tract; liver; kidneys; blood

skin

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, nausea, shortness of breath, sore throat

Skin: may be absorbed, redness, pain, local discoloration

Eyes: redness, pain

Ingestion: abdominal pain, nausea, vomiting, weakness

2,3,5,6-TETRACHLOROPHENOL     935-95-5

Inhalation: cough, sore throat

Skin: may be absorbed, redness, pain

Eyes: redness, pain

Ingestion: abdominal pain, diarrhoea, dizziness, headache, nausea, fatigue, muscular spasms, increased body temperature and sweating

2,3,5-TRICHLOROPHENOL     933-78-8

skin

Inhalation: cough, sore throat

Skin: redness, pain

Eyes: redness, pain

Ingestion: convulsion, abdominal pain, diarrhoea, dizziness, headache, vomiting, weakness, fatigue, muscular spasms, increased body temperature and sweating

2,3,6-TRICHLOROPHENOL     933-75-5

eyes; skin; resp. tract

skin

Inhalation: cough, sore throat

Skin: redness, pain

Eyes: redness, pain

Ingestion: abdominal pain, diarrhoea, dizziness, headache, vomiting, weakness, fatigue, muscular spasms, increased body temperature and sweating

2,4,5-TRICHLOROPHENOL     95-95-4

eyes; skin; resp. tract

skin; liver; kidneys

Inhalation: cough, sore throat

Skin: may be absorbed, redness

Eyes: redness, blurred vision

Ingestion: abdominal pain, diarrhoea, dizziness, headache, vomiting, weakness, fatigue, sweating

2,4,6-TRICHLOROPHENOL     88-06-2

eyes; skin; resp. tract

liver

Inhalation: cough

Skin: may be absorbed, redness

Eyes: redness

Ingestion: diarrhoea, nausea, vomiting, weakness

 

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Read 3669 times Last modified on Friday, 09 December 2011 18:24