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Thursday, 18 August 2011 04:59

Nitrocompounds, Aromatic: Health Hazards

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Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

1-CHLORO-2,4-DINITROBEN­ZENE    97-00-7

eyes; skin; resp tract

skin; eyes

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing, nausea, vomiting, disturbed vision 

Skin: may be absorbed, redness, pain  

Eyes: redness, pain  

Ingestion: abdominal pain, blue skin, dizziness, headache, laboured breathing, nausea, vomiting

1-CHLORO-2-NITROBENZENE 88-73-3

eyes; skin; resp tract; blood

blood; liver; kidneys; spleen

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, nausea, shortness of breath

Skin: may be absorbed, redness

Eyes: redness, pain

1-CHLORO-4-NITROBENZENE 100-00-5

blood

skin; blood

Inhalation: headache, faintness, vertigo, weakness    

Skin: may be absorbed

Blood; liver; kidneys; CVS; spleen; bone marrow; repro sys (in animals: vascular & liver tumors) Inh; abs; ing; con

Anoxia; unpleasant taste; anemia; methemo; in animals: hema, hemog; spleen, kidney, bone marrow changes; repro effects; (carc)

1,2-DICHLORO-3-NITROBEN­ZENE    3209-22-1

blood

skin; liver; kidneys

Inhalation: blue lips or finger nails  

Skin: may be absorbed, redness, blue lips, blue fingernails

Ingestion: blue lips or fingernails, blue skin, confusion, headache, vomiting, weakness

1,2-DICHLORO-4-NITROBEN­ZENE    99-54-7

eyes; skin; resp tract; lungs

skin; kidneys; liver

Inhalation: blue lips or finger nails, burning sensation of the throat, headache, shortness of breath

Skin: may be absorbed, redness, burning sensation, pain, blue lips or fingernails  

Eyes: redness, pain      

Ingestion: blue lips or fingernails

2,4-DICHLORO-1-NITROBEN­ZENE    611-06-3

blood

liver; kidneys

Inhalation: blue lips or finger nails

Skin: may be absorbed, redness, blue lips, blue fingernails    

Eyes: redness

Ingestion: blue lips or fingernails, blue skin, confusion, headache, vomiting, weakness

1,3-DINITROBENZENE     99-65-0

eyes; skin; resp tract

liver; may impair male fertility

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing, weakness, burning sensation in the mouth, dry throat, thirst, disturbed vision  

Skin: may be absorbed, redness, skin burns, yellowing of skin

Eyes: redness, burns      

Ingestion: abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

Blood; liver; CVS; eyes; CNS; skin Inh; abs; ing; con

Anoxia, cyan; vis dist, central scotomas; bad taste, burning mouth, dry throat, thirst; yellowing hair, skin; anemia; liver damage

DINITROBENZENE     25154-54-5

eyes; skin; resp tract; lungs; blood

liver; may impair male fertility

Inhalation: blue lips or finger nails, blue skin, burning sensation, dizziness, headache, laboured breathing, sore throat, weakness, disturbed vision

Skin: may be absorbed, redness, yellowing of skin

Eyes: redness

Ingestion: abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

o-DINITROBENZENE     528-29-0

eyes; skin; resp tract; lungs; blood

liver

Inhalation: blue lips or finger nails, blue skin, burning sensation, dizziness, headache, laboured breathing, weakness, disturbed vision

Skin: may be absorbed      

Eyes: redness

Ingestion: Abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

Blood; liver; CVS; eyes; CNS; skin Inh; abs; ing; con

Anoxia, cyan; vis dist, central scotomas; bad taste, burning mouth, dry throat, thirst; yellowing hair, skin; anemia; liver damage

p-DINITROBENZENE     100-25-4

eyes; skin; resp tract

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing, weakness, burning sensation in the mouth, dry throat, thirst, disturbed vision

Skin: may be absorbed, redness, yellowing of skin

Eyes: redness, burns      

Ingestion: abdominal pain, blue skin, diarrhoea, dizziness, headache, laboured breathing, nausea, vomiting

Blood; liver; CVS; eyes; CNS; skin Inh; abs; ing; con

Anoxia, cyan; vis dist, central scotomas; bad taste, burning mouth, dry throat, thirst; yellowing hair, skin; anemia; liver damage

2,4-DINITROPHENOL       51-28-5

GI tract

skin; CNS; blood; eyes;

Inhalation: sweating, palpitations, nausea, vomiting, collapse and death Skin: may be absorbed

DINITROTOLUENE     25321-14-6

blood

liver; male and female fertility

Inhalation: drowsiness, nausea, vomiting, weakness    

Skin: may be absorbed, blue lips or fingernails, blue skin, methemoglobin skin

Blood; liver; CVS; repro sys (in animals: liver, skin & kidney tumors) Inh; abs; ing; con

Anoxia, cyan; anemia, jaun; repro effects (carc)

2,3-DINITROTOLUENE     602-01-7

CNS; CVS; blood

Skin: may be absorbed

Ingestion: blue lips or fingernails; headache, nausea, sore throat; vomiting

2,4-DINITROTOLUENE     121-14-2

CNS; CVS; blood

Inhalation: blue lips or fingernails, headache, nausea, sore throat, vomiting  

Skin: may be absorbed Ingestion: blue lips or fingernails, headache, nausea, sore throat, vomiting

2,6-DINITROTOLUENE     606-20-2

blood

possibly carcinogenic to humans

Inhalation: blue lips or finger nails, blue skin, diarrhoea, dizziness, drowsiness    

Skin: may be absorbed

3,4-DINITROTOLUENE     610-39-9

CNS; CVS; blood;

Skin: may be absorbed

Ingestion: blue lips or fingernails, headache, nausea, sore throat, vomiting

NITROBENZENE 98-95-3

eyes; blood; CNS

skin; blood; liver; CNS; spleen; may impair male fertility

Inhalation: blue lips or finger nails, blue skin, dizziness, headache, nausea, unconsciousness, weakness  

Skin: may be absorbed

Blood; liver; kidneys; CVS; skin; eyes; repro sys Inh; abs; ing; con

Irrit eyes, skin, anoxia; derm; anemia; methemo; in animals: liver, kidney damage; testicular effects

4-NITRODIPHENYLAMINE     836-30-6

eyes; skin; resp tract; blood; brain

blood

Inhalation: burning sensation, cough, sore throat, see ingestion    

Skin: see ingestion    

Eyes: redness, pain    

Ingestion: blue lips or fingernails, blue skin, dizziness, headache, laboured breathing

NITROFEN         1836-75-5

eyes; skin; resp tract

skin; blood; CNS; human reproduction system

Inhalation: cough, laboured breathing, sore throat        

Skin: redness, pain          

Eyes: redness, pain, blurred vision  

Ingestion: abdominal pain

o-NITROTOLUENE           88-72-2

eyes; skin; resp tract; blood

liver; blood

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, sore throat        

Skin: may be absorbed, redness, pain

Eyes: redness, pain    

Ingestion: abdominal pain, blue lips or fingernails, blue skin, dizziness, headache, laboured breathing

Blood; CNS; CVS; skin; GI tract Inh; abs; ing; con

Anoxia, cyan; head, weak, dizz; ataxia; dysp; tacar; nau, vomit

p-NITROPHENOL     100-02-7

eyes; skin; resp tract; CNS; blood; kidneys

CNS; liver; kidneys; blood;

Inhalation: blue skin, dizziness, headache, fever, nausea, shortness of breath, weakness, perspiration

Skin: may be absorbed, redness, scabs

Eyes: redness, pain    

Ingestion: burning pain in mouth and throat, abdominal pain, dizziness, unconsciousness

p-NITROTOLUENE           99-99-0

eyes; skin; resp tract

liver; kidneys

Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, sore throat        

Skin: may be absorbed, redness, pain

Eyes: redness, pain    

Ingestion: abdominal pain, blue lips or fingernails, blue skin, dizziness, headache, laboured breathing, sore throat, unconsciousness

Blood; CNS; CVS; skin; GI tract Inh; abs; ing; con

Anoxia, cyan; head, weak, dizz; ataxia; dysp; tacar; nau, vomit

PICRIC ACID      88-89-1

eyes; skin

skin

Inhalation: cough, sore throat, weakness

Skin: may be absorbed, redness    

Eyes: redness, pain    

Ingestion: diarrhoea, dizziness, headache, nausea, vomiting

Kidneys; liver; blood; skin; eyes Inh; abs; ing; con

Irrit eyes, skin; sens derm; yellow-stained hair, skin; weak, myalgia, anuria, polyuria; bitter taste, GI dist; hepatitis, hema, album, neph

TETRYL 479-45-8

eyes; skin; resp tract; kidneys; liver; blood

skin

Inhalation: sleeplessness, cough, headache, sore throat, nosebleeds

Skin: redness, yellow stains of skin and hair

Eyes: redness, pain    

Ingestion: abdominal pain, dizziness, headache, nausea

Resp sys; eyes; CNS; skin; liver; kidneys Inh; abs; ing; con

Sens derm, itch, eryt; edema on nasal folds, cheeks, neck; kera; sneez; anemia; ftg; cough, coryza; irrity; mal, head, lass, insom; nau, vomit; liver, kidney damage

2,4,6-TRINITROTOLUENE     118-96-7

eyes; skin; resp tract; blood

liver; blood; eyes

Eyes: redness, pain

Blood; liver; eyes; CVS; CNS; kidneys; skin; resp sys Inh; abs; ing; con

Irrit skin, muc memb; liver damage, jaun; cyan; sneez; cough, sore throat; peri neur, musc pain; kidney damage; cataract; sens derm; leucyt; anemia; card irreg

 

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Read 5494 times Last modified on Friday, 09 December 2011 18:05