Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

ACETAMIDE       60-35-5

eyes; skin; resp tract

Inhalation: cough, shortness of breath

Skin: redness, pain

Eyes: pain, redness, blurred vision

Ingestion: sore throat, burning sensation

2-ACETYLAMINOFLUORENE     53-96-3

Liver; bladder; kidneys; pancreas; skin; lungs (in animals: tumors of the liver; bladder, pancreas, skin & lungs) Inh, abs, ing, con

Reduced function of liver, kidneys, bladder, pancreas (carc)

ACRYLAMIDE     79-06-1

skin; resp tract; CNS; liver

PNS; CNS

Inhalation: cough, sore throat, weakness

Skin: may be absorbed, redness, pain

Eyes: redness, pain

Ingestion: abdominal pain, weakness

CNS; PNS; skin; eyes, repro sys (in animals: tumors of the lungs, testes, thyroid & adrenal glands) Inh, abs, ing, con

Irrit eyes, skin; ataxia, numb limbs, pares; musc weak; absent deep tendon reflex; hand sweat; ftg, leth; repro effects (carc)

2-CHLOROACETAMIDE    79-07-2

eyes; skin; resp tract; heart; liver; spleen

skin

Inhalation: burning sensation, cough, sore throat

Skin: redness, pain

Eyes: redness, pain

Ingestion: sore throat

CYCLOPHOSPHAMIDE    50-18-0

eyes; skin; resp tract; kidneys; bladder; CVS; CNS; GI tract; liver; heart; blood

skin

Inhalation: diarrhoea, dizziness, loss of hair, darkening of skin and finger nails, nausea, vomiting

Skin: may be absorbed

DIMETHYL ACETAMIDE     127-19-5

eyes; skin; resp tract

skin; liver; kidneys

Inhalation: headache, nausea, vomiting

Skin: may be absorbed, redness

Eyes: Vapour will be absorbed, redness, pain

CNS; liver; skin Inh, abs, ing, con

irrit skin; jaun, liver damage; depres, leth, halu, delusions

DIMETHYLFORMAMIDE    68-12-2

eyes; skin; resp tract; liver; CNS

liver

Inhalation: loss of appetite, abdominal pain, diarrhoea, dizziness, nausea, vomiting, nervous agitation, facial flushing and alcohol intolerance

Skin: may be absorbed, dry skin, redness, roughness

Eyes: redness, pain

Eyes; liver; kidneys; CVS; skin; resp sys Inh, abs, ing, con

Irrit eyes, skin, resp sys; nau, vomit, colic; liver damage, enlarged liver; high BP; face flush; derm; in animals: kidney, heart damage

FORMAMIDE      75-12-7

lungs; CNS

liver

Inhalation: drowsiness, headache, nausea, unconsciousness

Skin: may be absorbed, redness

Eyes: redness

Ingestion: abdominal pain

Eyes; skin; resp sys; CNS; repro sys Inh, ing, con

Irrit eyes, skin, muc memb; drow, ftg; nau, acidosis; skin eruptions; in animals: repro effects