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Chemical Name CAS-Number |
ICSC Short-Term Exposure |
ICSC Long-Term Exposure |
ICSC Routes of Exposure and Symptoms |
US NIOSH Target Organs & Routes of Entry |
US NIOSH Symptoms |
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4-AMINODIPHENYL 92-67-1 |
eyes; bladder |
Inhalation: dullness, headache Skin: may be absorbed Eyes: redness |
Bladder; skin (bladder cancer)Inh; abs; ing; con |
Head, dizz; leth, dysp; ataxia, weak; methemo; urinary burning; acute hemorrhagic cystitis; (carc) |
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o-AMINOPHENOL 95-55-6 |
blood |
skin |
Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, unconsciousness, symptoms may be delayed Eyes: Redness |
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ANILINE 62-53-3 |
eyes; blood; CNS |
liver; kidneys; spleen; skin; blood |
Inhalation: blue lips or finger nails, blue skin, headache, dizziness, laboured breathing, convulsions, increased heartbeat, vomiting, weakness, unconsciousness Skin: may be absorbed Eyes: redness |
Blood; CVS; eyes; liver; kidneys; resp sys (in animals: tumors of the spleen) Inh; abs; ing; con |
Head, weak, dizz; cyan; ataxia; dysp on effort; tacar; irrit eyes; methemo; cirr; (carc) |
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ANILINE HYDROCHLORIDE 142-04-1 |
eyes; skin; resp tract; blood |
skin; spleen; kidneys; blood |
Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, nausea, shortness of breath, sore throat, unconsciousness, vomiting, weakness Skin: may be absorbed, redness Eyes: redness, pain Ingestion: abdominal pain |
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o-ANISIDINE 90-04-0 |
blood |
blood |
Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, nausea, vomiting Skin: may be absorbed |
Blood; kidneys; liver; CVS; CNSInh; abs; ing; con |
Head, dizz; cyan; RBC Heinz bodies; (carc) |
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p-ANISIDINE 104-94-9 |
blood |
blood |
Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, vomiting Skin: may be absorbed, blue lips or fingernails, blue skin Ingestion: blue lips or fingernails, blue skin |
Blood; kidneys; liver; CVS; CNSInh; abs; ing; con |
Head, dizz; cyan; RBC Heinz bodies; (carc) |
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BENZIDINE 92-87-5 |
Bladder; kidneys; liver; skin; blood (liver, kidney and bladder cancer) Inh; abs; ing; con |
Hema; secondary anemia from hemolysis; acute cystitis; acute liver disorders; derm; painful, irreg urination; (carc) |
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o-CHLOROANILINE 95-51-2 |
eyes; skin |
skin; liver; kidneys; blood |
Inhalation: blue lips or finger nails, blue skin, convulsions, diarrhoea, dizziness, headache, nausea, shortness of breath, vomiting, weakness Skin: may be absorbed, redness Eyes: redness, pain Ingestion: abdominal pain |
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m-CHLOROANILINE 108-42-9 |
eyes; skin; resp tract; liver; kidneys |
blood |
Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, nausea, shortness of breath, unconsciousness Skin: may be absorbed, redness, burning sensation Eyes: redness, pain, severe deep burns Ingestion: abdominal pain, |
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p-CHLOROANILINE 106-47-8 |
eyes; skin; resp tract; blood |
skin ; blood; liver; kidneys; spleen ; bone marrow |
Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing Skin: may be absorbed, redness Eyes: redness, pain Ingestion: nausea |
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2,4-DIAMINOTOLUENE 95-80-7 |
eyes; skin; resp tract; lungs; heart; liver; blood |
skin |
Inhalation: blue lips or finger nails, blue skin, dizziness, increased heart rate, laboured breathing, nausea, vomiting, convulsions, respiratory depression Skin: may be absorbed, redness on contact with molten material - skin burns, blisters Eyes: redness Ingestion: abdominal pain, blue skin, headache, nausea, vomiting |
Eyes, skin, resp sys, blood, CVS, liver, CNS (in animals: liver, skin & mammary gland tumors) Inh; abs; ing; con |
Irrit eyes, skin, nose, throat; derm; ataxia, tacar, nau, vomit, convuls, resp depres; methemo, cyan, head, ftg, dizz, bluish skin; liver inj; (carc) |
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2,6-DIAMINOTOLUENE 823-40-5 |
eyes; skin; resp tract; blood |
skin |
Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, shortness of breath Skin: redness Eyes: redness, pain Ingestion: laboured breathing |
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2,3-DICHLOROANILINE 608-27-5 |
liver; kidneys |
skin ; blood |
Inhalation: blue lips or finger nails, blue skin, convulsions, diarrhoea, dizziness, headache, shortness of breath, vomiting, weakness Skin: may be absorbed, redness Eyes: redness, pain |
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2,4-DICHLOROANILINE 554-00-7 |
liver; kidneys |
skin ; blood |
Inhalation: blue skin, dizziness, headache, shortness of breath Skin: may be absorbed, redness, skin burns Eyes: redness, pain, severe deep burns Ingestion: abdominal pain, nausea |
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2,5-DICHLOROANILINE 95-82-9 |
liver; kidneys |
skin ; blood |
Inhalation: blue skin, dizziness, headache, shortness of breath Skin: may be absorbed, redness, skin burns Eyes: redness, pain, severe deep burns Ingestion: abdominal pain, nausea |
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2,6-DICHLOROANILINE 608-31-1 |
liver; kidneys |
skin ; blood |
Inhalation: blue skin, dizziness, headache, shortness of breath Skin: may be absorbed, redness Eyes: redness, pain |
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3,4-DICHLOROANILINE 95-76-1 |
liver; kidneys |
skin; blood |
Inhalation: blue skin, dizziness, headache, shortness of breath Skin: may be absorbed, redness, burning sensation Eyes: redness, pain, severe deep burns Ingestion: abdominal pain, nausea |
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3,3'-DICHLOROBENZIDINE 91-94-1 |
resp tract |
skin; liver |
Inhalation: cough, sore throat Skin: may be absorbed |
Bladder; liver; lung ; skin; GI tract (in animals: liver & bladder cancer) Inh; abs; ing; con |
Skin sens, derm; head, dizz; caustic burns; frequent urination, dysuria; hema; GI upset; upper resp infection; (carc) |
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DIMETHYLANILINE 121-69-7 |
blood |
skin |
Inhalation: abdominal pain, blue skin, dizziness, headache, ringing in the ears, laboured breathing, unconsciousness, vomiting, visual disturbance Skin: may be absorbed, redness Eyes: redness, pain |
Blood; kidneys;liver; CVSInh; abs; ing; con |
Anoxia US NIOSH Symptoms; cyan, weak, dizz, ataxia; methemo |
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DIMETHYLAMINOAZOBENZENE 60-11-7 |
Skin; resp sys; liver; kidneys; bladder ( in animals: liver & bladder tumors) Inh; abs; ing; con |
Enlarged liver; liver, kidney dysfunc; contact derm; cough, wheez, dysp; bloody sputum; bronchial secretions; frequent urination, hema, dysuria; (carc) |
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N,N-DIMETHYL-p-TOLUIDINE 99-97-8 |
blood; brain; kidneys |
Inhalation: blue lips or finger nails, blue skin, dizziness, headache, shortness of breath, weakness Skin: may be absorbed |
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2,4-DINITROANILINE 97-02-9 |
eyes; skin; resp tract; blood |
blood |
Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, nausea, sore throat Skin: may be absorbed, redness, blue lips or fingernails, blue skin Eyes: redness, pain Ingestion: unconsciousness |
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DIPHENYLAMINE 122-39-4 |
eyes; skin; resp tract |
kidneys |
Inhalation: cough, sore throat Skin: redness Eyes: redness |
Eyes; skin; resp sys; CVS; blood; bladder; repro sysInh; abs; ing; con |
Irrit eyes, skin muc memb; eczema; tacar, hypertension; cough, sneez; methemo; incr BP, heart rate; prot, hema, bladder inj; in animals: terato effects |
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N-ISOPROPYLANILINE 768-52-5 |
skin; blood; brain; kidneys |
skin ; blood |
Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing Skin: may be absorbed, blue lips or fingernails, blue skin Eyes: redness, pain, blurred vision Ingestion: nausea |
Eyes; skin; resp sys; blood; CVS; liver; kidneysInh; abs; ing; con |
Irrit eyes, skin; head, weak, dizz; cyan; ataxia; dysp on effort; tacar; methemo |
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N-ISOPROPYL-N'-PHENYL-p-PHENYLENEDIAMINE 101-72-4 |
eyes; skin |
skin |
Inhalation: cough, irritant Skin: redness, irritant Eyes: redness, irritant |
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METHYLANILINE 100-61-8 |
eyes; skin; resp tract; blood; brain; kidneys |
skin; blood |
Inhalation: blue lips or finger nails, blue skin, cough, dizziness, headache, laboured breathing, sore throat Skin: may be absorbed, redness, pain Eyes: redness, pain, blurred vision Ingestion: abdominal pain, blue lips or fingernails, blue skin, dizziness, headache, laboured breathing, nausea |
Resp sys; liver; kidneys; blood; CNSInh; abs; ing; con |
Weak, dizz, head; dysp, cyan; methemo; pulm edema; liver, kidney damage |
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1,5-NAPHTHALENEDIAMINE 2243-62-1 |
skin |
Skin: may be absorbed |
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a-NAPHTHYLAMINE 134-32-7 |
Bladder; skin (bladder cancer) Inh; abs; ing; con |
Derm; hemorrhagic cystitis; dysp, ataxia, methemo; hema; dysuria; (carc) |
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b-NAPHTHYLAMINE 91-59-8 |
Bladder; skin (bladder cancer) Inh; abs; ing; con |
Derm; hemorrhagic cystitis; dysp; ataxia; methemo, hema; dysuria; (carc) |
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o-NITROANILINE 88-74-4 |
blood |
Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, shortness of breath, unconsciousness, weakness Skin: may be absorbed, blue lips or fingernails, blue skin |
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m-NITROANILINE 99-09-2 |
blood |
Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, shortness of breath, unconsciousness, weakness Skin: may be absorbed, blue lips or fingernails, blue skin |
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p-NITROANILINE 100-01-6 |
blood |
liver |
Inhalation: blue lips or finger nails, blue skin, dizziness, drowsiness, headache, laboured breathing, nausea, shortness of breath, unconsciousness, weakness Skin: may be absorbed, blue lips or fingernails, blue skin |
Resp sys; blood; heart; liver; abs; ing; con |
Irrit nose, throat; cyan, ataxia; tacar, tachypnea; dysp; irrity; vomit, diarr; convuls; resp arrest; anemia; methemo; jaundice |
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N-PHENYL-1-NAPHTHYLAMINE 90-30-2 |
skin |
Skin: redness |
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p-PHENYLENEDIAMINE 106-50-3 |
resp tract; blood; kidneys |
skin; resp tract |
Inhalation: cough, dizziness, headache, laboured breathing Skin: redness Eyes: redness, blurred vision, even permanent loss of vision Ingestion: abdominal pain, blue lips or fingernails, blue skin, vomiting, weakness, convulsions, coma, death |
Resp sys ; skinInh; abs; ing; con |
Irrit pharynx, larynx; bronchial asthma; sens derm |
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p-PHENYLENEDIAMINE HYDROCHLORIDE 624-18-0 |
eyes; skin; resp tract; blood; brain; kidneys |
skin; resp tract; liver |
Inhalation: cough, dizziness, laboured breathing, see ingestion Skin: redness Eyes: blurred vision, even permanent loss of vision Ingestion: abdominal pain, blue lips or fingernails, blue skin, vomiting, weakness, swelling of the face and neck, convulsions, coma, death |
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o-TOLIDINE 119-93-7 |
eyes; skin; resp tract |
skin; blood |
Inhalation: cough, weak irritant Skin: may be absorbed |
Eyes; resp sys; liver; kidneys; (in animals: liver, bladder & mammary gland tumors)Inh; abs; ing; con |
Irrit eyes, nose; in animals: liver, kidney damage; (carc) |
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o-TOLUIDINE 95-53-4 |
Eyes; skin; blood; kidneys; liver; CVS (in animals: liver, bladder & mammary gland tumors) Inh; abs; ing; con |
Irrit eyes; anoxia, head, cyan; weak, dizz, drow; micro hema, eye burns; derm; (carc) |
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XYLIDINE 1300-73-8 |
eyes; skin; resp tract; blood |
kidneys; liver; red blood cells |
Inhalation: blue lips or finger nails, blue skin, dizziness, headache, laboured breathing Skin: may be absorbed Eyes: redness, pain, blurred vision Ingestion: blue lips or fingernails, blue skin, dizziness, headache |
Resp sys; blood; liver; kidneys; CVSInh; abs; ing; con |
Anoxia, cyan, methemo; lung, liver, kidney damage |