Chemical Name

CAS-Number

ICSC Short-Term Exposure

ICSC Long-Term Exposure

ICSC Routes of Exposure and Symptoms

US NIOSH Target Organs & Routes of Entry

US NIOSH Symptoms

ACETONITRILE   75-05-8

eyes; skin; resp tract

Inhalation: abdominal pain, convulsions, laboured breathing, sore throat, unconsciousness, vomiting, weakness, symptoms may be delayed

Skin: may be absorbed, redness

Eyes: redness, pain

Kidneys; liver; CVS; CNS; lungs; skin; eyes; resp sys Inh; abs; ing; con

Irrit nose, throat; asphy; nau, vomit; chest pain; weak; stupor, convuls; in animals: liver, kidney damage

ACRYLONITRILE 107-13-1

eyes; skin; resp tract; liver; CNS

CNS; liver

Inhalation: dizziness, headache, nausea, vomiting, weakness, tremor and uncoordinated movements

Skin: may be absorbed, redness, pain, blisters

Eyes: redness, pain, blurred vision

Ingestion: abdominal pain, headache, nausea, shortness of breath, vomiting, weakness

CVS; liver; kidneys; CNS; skin; brain; lungs; bowels; eyes Inh; abs; ing; con

Irrit eyes, skin; asphy; head; sneez; nau, vomit; weak, li-head; skin vesic; scaling derm; (carc)

ALLYL ISOTHIOCYANATE     57-06-7

eyes; skin; resp tract

skin

Inhalation: sore throat, cough, laboured breathing

Skin: redness, pain

Eyes: pain, redness, blurred vision

Ingestion: sore throat, burning sensation, nausea, vomiting

BENZONITRILE   100-47-0

eyes; resp tract;

Inhalation: headache, laboured breathing, unconsciousness

Eyes: redness, painIngestion: nausea, vomiting

CALCIUM CYANIDE         592-01-8

eyes; skin; resp tract; lungs; CNS; blood; heart

skin; reproduction

Inhalation: burning sensation, cough, dizziness, headache, red colouration of the skin, laboured breathing, nausea, shortness of breath, unconsciousness, vomiting, convulsions, coma, death

Skin: may be absorbed, skin burns, pain, itching, papules

Eyes: pain, blurred vision, possible permanent loss of vision, severe deep burns

Ingestion: confusion, burning sensation in the mouth, numbness or tightness in throat, salivation, convulsions followed by paralysis

CHLOROACETONITRILE  107-14-2

eyes; skin; resp tract

Inhalation: cough, headache, laboured breathing, sore throat, unconsciousness

Skin: may be absorbed, redness

Eyes: redness

Ingestion: burning sensation

o-CHLOROBENZYLIDENE MALONONITRILE            2698-41-1

Resp sys; skin; eyes Inh; abs; ing; con

Pain, burn eyes, lac, conj; eryt eyelids, blepharospasm; irrit throat, cough, chest tight; head; eryt, vesic skin

CYANAMIDE       420-04-2

eyes; skin; resp tract

skin; reproduction

Inhalation: cough, shortness of breath

Skin: may be absorbed, redness

Eyes: redness, pain

Ingestion: abdominal pain

Eyes; skin; resp sys; CNS Inh; abs; ing; con

Irrit eyes, skin, resp sys; eye, skin burns; miosis, salv, lac, twitch; Antabuse-like effects

CYANOGEN BROMIDE     506-68-3

eyes; skin; resp tract; lungs

lungs

Inhalation: abdominal pain, burning sensation, confusion, convulsions, dizziness, headache, laboured breathing, shortness of breath, unconsciousness, vomiting, asphyxia, anxiety, irregular heartbeat

Skin: may be absorbed, redness, pain, blisters

Eyes: redness, pain, severe deep burns, tear drawing

Ingestion: abdominal cramps, burning sensation

CYANOGEN CHLORIDE   506-77-4

eyes; skin; resp tract; lungs; skin

Inhalation: confusion, drowsiness, nausea, sore throat, irritation, unconsciousness, vomiting, symptoms may be delayed

Skin: redness, pain, the liquid may be absorbed, on contact with liquid: frostbite

Eyes: on contact with liquid: frostbite, redness, pain

Eyes; skin; resp sys; CNS; CVS Inh; abs (liq); con (liq)

Irrit eyes, upper resp sys; cough, delayed pulm edema; weak, head, gidd, dizz, conf, nau, vomit; irreg heartbeat; irrit skin (liq)

DICYANODIAMIDE          461-58-5

Inhalation: abdominal pain, dizziness, nausea, shortness of breath

Skin: redness, skin burns

Eyes: loss of vision, severe deep burns

HYDROGEN CYANIDE     74-90-8

Inhalation: numbness or tightness in throat and stiffness in lower jaw, confusion, dizziness, headache, laboured breathing, nausea, unconsciousness, vomiting, weakness

Skin: may be absorbed

Eyes: vapour will be absorbed, see inhalation

Ingestion: burning sensation

CVS; CNS; thyroid; blood Inh; abs; ing; con

Asphy; weak, head, conf; nau, vomit; incr rate and depth of respiration or respiration slow and gasping; thyroid, blood changes

2-HYDROXY-2-METHYLPROPIONITRILE 75-86-5

eyes; skin; resp tract; intracellular oxygen metabolism

Inhalation: confusion, dizziness, headache, laboured breathing, nausea, unconsciousness, vomiting, weakness

Skin: may be absorbed, redness

Eyes: redness

Ingestion: confusion, dizziness, laboured breathing, unconsciousness, vomiting

Eyes; skin; resp sys; CNS; CVS; liver; kidneys; GI tract Inh; abs; ing; con

Irrit eyes, skin, resp sys; dizz, weak, head, conf, convuls; liver, kidney inj; pulm edema, asphy

IODINE CYANIDE            506-78-5

eyes; skin; resp tract; lungs; intracellular oxygen metabolism

Inhalation: confusion, cough, dizziness, headache, laboured breathing, nausea, unconsciousness, vomiting, weakness

Skin: may be absorbed, redness

Eyes: redness

Ingestion: confusion, dizziness, laboured breathing, unconsciousness, vomiting

POTASSIUM CYANIDE     151-50-8

eyes; skin; resp tract

thyroid gland

Inhalation: confusion, convulsions, dizziness, headache, laboured breathing, nausea, shortness of breath, unconsciousness, vomiting, weakness, asphyxiant, anxiety, irregular heart beat, tightness in the chest

Skin: may be absorbed, redness

Eyes: vapour will be absorbed, redness

Ingestion: salivation, abdominal cramps, burning sensation

CVS; CNS; eyes; skin; thyroid; blood Inh; abs; ing; con

Irrit eyes, skin; asphy; weak, head, conf; nau, vomit; incr resp rate; slow gasping respiration; thyroid, blood changes

PROPIONITRILE 107-12-0

eyes; skin; resp tract; cellular metabolism; CNS

skin; birth defects

Inhalation: confusion, asphyxia dizziness, dullness, headache, nausea, vomiting

Skin: may be absorbed, dry skin, pain

Eyes: severe deep burns

Ingestion: unconsciousness

Eyes; skin; resp sys; CNS; CNS; liver; kidneys Inh; abs; ing; con

Irrit eyes, skin, resp sys; nau, vomit; chest pain; weak; stupor; convuls; in animals: liver, kidney damage

SODIUM CYANIDE          143-33-9

Inhalation: burning sensation, headache, shortness of breath, sore throat, unconsciousness, weakness, seizure

Skin: may be absorbed, skin burns, burning sensation, pain

Eyes: pain, severe deep burns

Ingestion: abdominal cramps, diarrhoea, vomiting

CVS; CNS; eyes; skin; thyroid; blood Inh; abs; ing; con

Irrit eyes, skin; asphy; weak, head, conf; nau, vomit; incr resp rate; slow gasping respiration; thyroid, blood changes

TETRAMETHYLSUCCINONITRILE     3333-52-6

CNS

Skin: Inhalation: convulsions, dizziness, headache, nausea, unconsciousness, vomitingmay be absorbed

CNS; liver; kidneys; GI tract Inh; abs; ing; con

Head, nau; convuls, coma; liver, kidney, GI effects